Leading Manufacturer and Trader from Chandigarh, our product range includes Pharmaceutical Injections such as Artemether Injection, Atmobolic 25mg Injection, Atmobolic 50mg Injcetion, Atmocin 100 Injection, Atmocin 250 Injection, Atmocin 500 Injection and many more items.
Ceftriaxone is a beta-lactam antibiotic like the penicillins with bactericidal action. Penicillin-binding proteins (PBPs) are responsible for several steps in the synthesis of the cell wall of bacteria and are found in large quantities.Ceftriaxone inhibits the third and final stage of bacterial cell wall synthesis by preferentially binding to the specific PBPs located inside the bacterial cell wall. Ceftriaxone interferes with PBP-mediated cell wall synthesis leading to cell lysis, which is mediated by bacterial cell wall autolytic enzymes (autolysins), possibly through interference with an autolysin inhibitor. The presence of an aminothiazolyl-acetyl side chain with an alphaâ€”methoxyimino group at the 7-position of the beta-lactam ring provides Ceftriaxone with enhanced antibacterial activity, particularly against the Enterobacteriaceae (e.g., E. coli, Klebsiella, Proteus, and Serratia) and increased stability against many of the beta-lactamases. Many strains of Pseudomonas aeruginosa are susceptible to Ceftriaxone. Other susceptible gram-negative organisms include Enterobacter, Citrobacter, Morganella, Providencia, Moraxella (Branhamella) catarrhalis, and N. meningitidis. Ceftriaxone has exceptional activity against H. influenzae and N. gonorrhoeae and is the drug of choice for uncomplicated N. gonorrhoeae infections. Sulbactam, by irreversibly binding to the beta-lactamases produced by the common gram-positive or negative bacteria protects the beta-lactam ring of ceftriaxone, and conserves the activity. Thus on combining ceftriaxone with sulbactam, the combination product - Ceftriaxone & Sulbactam For Injection extends its utility in the treatment of broad range of infections caused by organisms resistant to the antibiotic alone, making them susceptible, possibly through lowering of MIC.
ATMOXON-S-1.5 GM/ Ceftriaxone 250 and sulbactum 125 mg
Our reputation in the market is largely attributable to our qualitative grade Atmobolic 50mg Injection from our extensive collection of injections. This injection is used in the treatment of osteoporosis in postmenopausal women. Our provided injection is well-processed using premium grade chemical compounds and progressive methodologies. This injection is highly demanded by our patrons owing to effectiveness and quick results. In addition to this, exact composition and safe packing increase the demand of the offered injection in the market.
Being the most respected organization guided by experienced and knowledgeable professionals, we provide a quality assured Atmocin 100 Injection. Widely demanded in the market, this injection is widely appreciated by our clients for its quick action and effectiveness. This injection is used to treat anaemia. The offered injection is processed using quality tested chemical compounds and ultra-modern techniques under the stern vigilance of adroit professionals.
Being one of the renowned organizations, we have been able to provide our precious clients a qualitative range of Atmobolic 25mg Injection. This injection is used to treat anemia in people with kidney failure. The provided injection is perfectly processed under the vigilance of adroit professionals using high grade chemical compounds and pioneered techniques. To ensure the best quality, this injection is duly examined against different parameters of quality.
We offer our clients the qualitative range of Artemether Injection. Our provided injection is used as treatment of fevers. This injection is widely acknowledged by our client for its purity and precise composition. This injection is well-processed under the supervision of skilled professionals using premium grade chemical compounds with the aid of sophisticated technology. In order to ensure its quality, this injection is duly tested by our quality experts against various parameters.
Ceftriaxone is completely absorbed following IM administration with mean maximum plasma concentration occurring between 2-3 hours post dose. Ceftriaxone achieves high concentrations in urine. 33% to 67% of ceftriaxone was excreted as unchanged drug and the remainder is excreted in bile and faeces. Elimination half life is 8.7 hours. Ceftriaxone is 98% bound to plasma proteins and Ceftriaxone crosses the blood brain barrier.
Tazobactam is metabolized to a single metabolite that lacks pharmacological and antibacterial activities. Tazobactam and its metabolite are eliminated primarily by renal excretion with 80 % of the ministered dose excreted as unchanged drug and the remainder as a single metabolite. Tazobactam is also secreted into the bile. Tazobactam is approximately 30% bound to plasma proteins. Protein binding of the tazobactam metabolite is negligible. Tazobactam is widely distributed into tissues and body fluids including intestinal mucosa, gall bladder, lung, female reproductive tissues, interstitial fluid and bile.