Approx. Rs 58 / Pack
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|Composition||Calcium Carbonate IP1250 mg Vitamin D3 IP250 IU|
|Packaging Size||10 x 15|
This combination medication is used to prevent or treat low blood calcium levels in people who do not get enough calcium from their diets. It may be used to treat conditions caused by low calcium levels such as bone loss (osteoporosis), weak bones (osteomalacia/rickets), decreased activity of the parathyroid gland (hypoparathyroidism), and a certain muscle disease (latent tetany). It may also be used in certain patients to make sure they are getting enough calcium (e.g., women who are pregnant, nursing, or postmenopausal, people taking certain medications such as phenytoin, phenobarbital, or prednisone). Calcium plays a very important role in the body. It is necessary for normal functioning of nerves, cells, muscle, and bone. If there is not enough calcium in the blood, then the body will take calcium from bones, thereby weakening bones. Vitamin D helps your body absorb calcium and phosphorus. Having the right amounts of vitamin D, calcium, and phosphorus is important for building and keeping strong bonesIndications
- Pregnant, nursing or postmenopausal women
- Normal functioning of nerves, muscles, cells, bones
Always get advice from a healthcare professional before taking this medicine if:
Pregnancy and breast-feeding:
- you are allergic or sensitive to or have had a reaction to any of the ingredients in the medicine
- this medicine is for a child or an adolescent
- you have a history of kidney stones or calcium deposits in your kidneys
- you have kidney problems
- you have high levels of calcium in your blood or urine, or this has been caused by having certain conditions such as hyperparathyroidism, cancer or bone tumours
- your osteoporosis is caused by being immobile
- you have vitamin D poisoning
- you have sarcoidosis
- you are taking calcium and vitamin D supplements
- you have a history of fructose intolerance, glucose-galactose malabsorption or sucrase-isomaltase insufficiency
This medicine is not known to cause any problems during pregnancy or while breast-feeding. However, as with all medicines, you should seek medical advice from your doctor before taking this medicine if you are pregnant or are breast-feeding.
Tablet may be taken with or without food.
Disclaimer:To be taken only after consulting with the doctor.
About 15-25% gets absorbed in the GI tract and converted to calcium chloride by gastric acid. Some of the calcium is absorbed in the intestines. Calcium is absorbed in soluble, ionized form; solubility of calcium is increased in an acidic environment.Vitamin D:
Well-absorbed in the GI tract in the presence of bile.Distribution
Crosses placenta, enters breast milk.
Vitamin D: Bound to a specific α-globulin and can be stored in adipose & muscle tissue for long periods of time. Slowly released from storage sites & skin where it is formed in the presence of sunlight or uv light. It may distribute into breast milk.Metabolism:
Vitamin D: Hydroxylated in the liver by the enzyme vitamin D 25-hydroxylase to form 25-hydroxycholecalciferol (calcifediol). Further hydroxylated in the kidneys by the enzyme vitamin D1-hydroxylase to form the active metabolites 1,25-dihydroxycholecalciferol (calcitriol). Then metabolism also occurs in the kidneys, including the formation of the 1,24,25-trihydroxy derivatives.Excretion:
Calcium Carbonate: Mainly in the faeces as unabsorbed calcium; urine (20%).
Vitamin D3: Mainly in the bile & faeces with only small amounts appearing in urine.